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Epigenetic changes in fibroblasts drive cancer metabolism and differentiation

Genomic changes that drive cancer initiation and progression contribute to the co-evolution of the adjacent stroma. The nature of the stromal reprogramming involves differential DNA methylation patterns and levels that change in response to the tumor and systemic therapeutic intervention. Epigenetic...

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Detalles Bibliográficos
Autores principales: Mishra, Rajeev, Haldar, Subhash, Suchanti, Surabhi, Bhowmick, Neil A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859444/
https://www.ncbi.nlm.nih.gov/pubmed/31627186
http://dx.doi.org/10.1530/ERC-19-0347