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Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim-3 and galectin-9, in cervical cancer

Persistent infection with high-risk human papillomavirus is known to cause cervical cancer. The binding of the costimulatory factors, Tim-3 and galectin-9, can cause immune tolerance and lead to immune escape during carcinogenesis. Epigenetic regulation is essential for Tim-3/galectin-9 expression,...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Tian, Sijuan, Pei, Meili, Zhao, Minyi, Wang, Li, Jiang, Yifan, Yang, Ting, Zhao, Juan, Song, Lihua, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859457/
https://www.ncbi.nlm.nih.gov/pubmed/31661141
http://dx.doi.org/10.3892/or.2019.7388