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Targeting RAD51 enhances chemosensitivity of adult T-cell leukemia-lymphoma cells by reducing DNA double-strand break repair

RAD51, is a key homologous recombination protein that repairs DNA damage and maintains gene diversity and stability. Previous studies have demonstrated that the over-expression of RAD51 is associated with chemotherapy resistance of tumor cells to chemotherapy, and enhanced activity of DNA damage rep...

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Detalles Bibliográficos
Autores principales: Yang, Meng, Tian, Xiaoxue, Fan, Zhuoyi, Yu, Wenlei, Li, Zheng, Zhou, Jie, Zhang, Wenjun, Liang, Aibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859462/
https://www.ncbi.nlm.nih.gov/pubmed/31638261
http://dx.doi.org/10.3892/or.2019.7384