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Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways

During neurogenesis, progenitors switch from self-renewal to differentiation through the interplay of intrinsic and extrinsic cues, but how these are integrated remains poorly understood. Here, we combine whole-genome transcriptional and epigenetic analyses with in vivo functional studies to demonst...

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Detalles Bibliográficos
Autores principales: Bonnefont, Jerome, Tiberi, Luca, van den Ameele, Jelle, Potier, Delphine, Gaber, Zachary B., Lin, Xionghui, Bilheu, Angéline, Herpoel, Adèle, Velez Bravo, Fausto D., Guillemot, François, Aerts, Stein, Vanderhaeghen, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859502/
https://www.ncbi.nlm.nih.gov/pubmed/31353074
http://dx.doi.org/10.1016/j.neuron.2019.06.027