Cargando…
Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways
During neurogenesis, progenitors switch from self-renewal to differentiation through the interplay of intrinsic and extrinsic cues, but how these are integrated remains poorly understood. Here, we combine whole-genome transcriptional and epigenetic analyses with in vivo functional studies to demonst...
Autores principales: | Bonnefont, Jerome, Tiberi, Luca, van den Ameele, Jelle, Potier, Delphine, Gaber, Zachary B., Lin, Xionghui, Bilheu, Angéline, Herpoel, Adèle, Velez Bravo, Fausto D., Guillemot, François, Aerts, Stein, Vanderhaeghen, Pierre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859502/ https://www.ncbi.nlm.nih.gov/pubmed/31353074 http://dx.doi.org/10.1016/j.neuron.2019.06.027 |
Ejemplares similares
-
CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
por: Van Heurck, Roxane, et al.
Publicado: (2023) -
Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation
por: Suzuki, Ikuo K., et al.
Publicado: (2018) -
Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way
por: Espuny-Camacho, Ira, et al.
Publicado: (2018) -
The Effects of Extrinsic and Intrinsic Factors on Neurogenesis
por: Jiang, Mei, et al.
Publicado: (2023) -
Cell-extrinsic requirement for sulfate in regulating hippocampal neurogenesis
por: Zhang, Zhe, et al.
Publicado: (2020)