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Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells

Cells employ multiple defence mechanisms to sustain a wide range of stress conditions associated with accumulation of modified self-biomolecules leading to lipo- and proteotoxicity. One of such mechanisms involves activation of the autophagy-lysosomal pathway for removal and degradation of modified...

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Detalles Bibliográficos
Autores principales: Coliva, Giulia, Duarte, Sofia, Pérez-Sala, Dolores, Fedorova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859560/
https://www.ncbi.nlm.nih.gov/pubmed/30737170
http://dx.doi.org/10.1016/j.redox.2019.101123