Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

The intermediate filament protein vimentin constitutes a critical sensor for electrophilic and oxidative stress, which induce extensive reorganization of the vimentin cytoskeletal network. Here, we have investigated the mechanisms underlying these effects. In vitro, electrophilic lipids, including 1...

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Detalles Bibliográficos
Autores principales: Mónico, Andreia, Duarte, Sofia, Pajares, María A., Pérez-Sala, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Structure-function relationships of protein lipoxidation and mechanisms of action
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859561/
https://www.ncbi.nlm.nih.gov/pubmed/30658903
http://dx.doi.org/10.1016/j.redox.2019.101098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859561/
https://www.ncbi.nlm.nih.gov/pubmed/30658903
http://dx.doi.org/10.1016/j.redox.2019.101098

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