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15-Keto prostaglandin E(2) suppresses STAT3 signaling and inhibits breast cancer cell growth and progression
Overproduction of prostaglandin E(2) (PGE(2)) has been linked to enhanced tumor cell proliferation, invasiveness and metastasis as well as resistance to apoptosis. 15-Keto prostaglandin E(2) (15-keto PGE(2)), a product formed from 15-hydroxyprostaglandin dehydrogenase-catalyzed oxidation of PGE(2),...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859578/ https://www.ncbi.nlm.nih.gov/pubmed/31129031 http://dx.doi.org/10.1016/j.redox.2019.101175 |