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Voltage gated proton channels modulate mitochondrial reactive oxygen species production by complex I in renal medullary thick ascending limb

Hv1 is a voltage-gated proton channel highly expressed in immune cells where, it acts to maintain NAD(P)H oxidase activity during the respiratory burst. We have recently reported that Hv1 is expressed in cells of the medullary thick ascending limb (mTAL) of the kidney and is critical to augment reac...

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Detalles Bibliográficos
Autores principales: Patel, Bansari, Zheleznova, Nadezhda N., Ray, Sarah C., Sun, Jingping, Cowley, Allen W., O'Connor, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859587/
https://www.ncbi.nlm.nih.gov/pubmed/31060879
http://dx.doi.org/10.1016/j.redox.2019.101191