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YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma

BACKGROUND: Dynamic N(6)-methyladenosine (m(6)A) modification was previously identified as a ubiquitous post-transcriptional regulation that affected mRNA homeostasis. However, the m(6)A-related epitranscriptomic alterations and functions remain elusive in human cancer. Here we aim to identify the p...

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Detalles Bibliográficos
Autores principales: Hou, Jiajie, Zhang, He, Liu, Jun, Zhao, Zhenjun, Wang, Jianye, Lu, Zhike, Hu, Bian, Zhou, Jiankui, Zhao, Zhicong, Feng, Mingxuan, Zhang, Haiyan, Shen, Bin, Huang, Xingxu, Sun, Beicheng, He, Chuan, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859620/
https://www.ncbi.nlm.nih.gov/pubmed/31735169
http://dx.doi.org/10.1186/s12943-019-1082-3