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Assessment of computational methods for the analysis of single-cell ATAC-seq data
BACKGROUND: Recent innovations in single-cell Assay for Transposase Accessible Chromatin using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of thousands of individual cells. scATAC-seq data analysis presents unique methodological challenges. scATAC-seq experiments sample DNA,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859644/ https://www.ncbi.nlm.nih.gov/pubmed/31739806 http://dx.doi.org/10.1186/s13059-019-1854-5 |