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The Effects of Progranulin in a Rat Model of Acute Myocardial Ischemia/Reperfusion are Mediated by Activation of the P13K/Akt Signaling Pathway

BACKGROUND: Progranulin is an adipokine, encoded by the progranulin (GRN) gene. Progranulin is expressed in atherosclerosis, but its effects in cardiac ischemia and reperfusion injury are unknown. Therefore, this study aimed to investigate the effects of progranulin in a rat model of acute myocardia...

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Detalles Bibliográficos
Autores principales: Alyahya, Asma Mohammed, Al-Masri, Abeer, Hersi, Ahmad, El Eter, Eman, Husain, Sufia, Lateef, Rahmatunnesa, Mawlana, Ola H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859783/
https://www.ncbi.nlm.nih.gov/pubmed/31695019
http://dx.doi.org/10.12659/MSMBR.916258