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Innate immune receptors for cross-presentation: The expanding role of NLRs

A critical role of pattern recognition receptors (PRRs) is to influence adaptive immune responses by regulating antigen presentation. Engagement of PRRs in dendritic cells (DCs) increases MHC class I antigen presentation and CD8(+) T-cell activation by cross-presented peptides but the molecular mech...

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Detalles Bibliográficos
Autores principales: Corridoni, Daniele, Simmons, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859786/
https://www.ncbi.nlm.nih.gov/pubmed/29198621
http://dx.doi.org/10.1016/j.molimm.2017.11.028