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Preferential interaction of MHC class I with TAPBPR in the absence of glycosylation
We recently discovered that TAPBPR promotes reglucosylation of the N-linked glycan on MHC class I molecules, a modification that restores their recognition by calreticulin and reincorporation into the peptide-loading complex. We wondered whether TAPBPR displayed some degree of glycan specificity, as...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859791/ https://www.ncbi.nlm.nih.gov/pubmed/30077416 http://dx.doi.org/10.1016/j.molimm.2018.06.269 |