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The expanding role of venetoclax in chronic lymphocytic leukemia and small lymphocytic lymphoma
The BCL-2 protein family members inhibit cellular apoptosis, and their overexpression represents a common survival adaption in cancer. Recently, a selective BCL-2 inhibitor ABT-199, venetoclax, has demonstrated remarkable activity in relapsed/refractory chronic lymphocytic leukemia/small lymphocytic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859801/ https://www.ncbi.nlm.nih.gov/pubmed/32009829 http://dx.doi.org/10.2147/BLCTT.S177009 |