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The expanding role of venetoclax in chronic lymphocytic leukemia and small lymphocytic lymphoma

The BCL-2 protein family members inhibit cellular apoptosis, and their overexpression represents a common survival adaption in cancer. Recently, a selective BCL-2 inhibitor ABT-199, venetoclax, has demonstrated remarkable activity in relapsed/refractory chronic lymphocytic leukemia/small lymphocytic...

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Detalles Bibliográficos
Autores principales:	Schieber, Michael, Ma, Shuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859801/ https://www.ncbi.nlm.nih.gov/pubmed/32009829 http://dx.doi.org/10.2147/BLCTT.S177009

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