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Exon size and sequence conservation improves identification of splice-altering nucleotides

Pre-mRNA splicing is regulated through multiple trans-acting splicing factors. These regulators interact with the pre-mRNA at intronic and exonic positions. Given that most exons are protein coding, the evolution of exons must be modulated by a combination of selective coding and splicing pressures....

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Detalles Bibliográficos
Autores principales: Movassat, Maliheh, Forouzmand, Elmira, Reese, Fairlie, Hertel, Klemens J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859846/
https://www.ncbi.nlm.nih.gov/pubmed/31554659
http://dx.doi.org/10.1261/rna.070987.119