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High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target

Anti-apoptotic protein-5 (API-5) is a survival protein interacting with the protein acinus, preventing its cleavage by caspase-3 and thus inhibiting apoptosis. We studied the effect of targeting API-5 in chemoresistant triple negative breast cancers (TNBCs), to reverse chemoresistance. 78 TNBC biops...

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Detalles Bibliográficos
Autores principales: Bousquet, Guilhem, Feugeas, Jean-Paul, Gu, Yuchen, Leboeuf, Christophe, Bouchtaoui, Morad El, Lu, He, Espié, Marc, Janin, Anne, Benedetto, Melanie Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859922/
https://www.ncbi.nlm.nih.gov/pubmed/31762939
http://dx.doi.org/10.18632/oncotarget.27312