The multifaceted anti-cancer effects of BRAF-inhibitors

The BRAF gene is commonly involved in normal processes of cell growth and differentiation. The BRAF (V600E) mutation is found in several human cancer, causing an increase of cell proliferation due to a modification of the ERK/MAPK-signal cascade. In particular, BRAFV600E mutation is found in those m...

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Detalles Bibliográficos
Autores principales: Croce, Laura, Coperchini, Francesca, Magri, Flavia, Chiovato, Luca, Rotondi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859927/
https://www.ncbi.nlm.nih.gov/pubmed/31762942
http://dx.doi.org/10.18632/oncotarget.27304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859927/
https://www.ncbi.nlm.nih.gov/pubmed/31762942
http://dx.doi.org/10.18632/oncotarget.27304

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