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IP10-CDR3 Reduces The Viability And Induces The Apoptosis Of Ovarian Cancer Cells By Down-Regulating The Expression Of Bcl-2 And Caspase 3

PURPOSE: This study aimed to explore the effects of interferon-γ inducible protein 10 (IP10) and complementarity-determining region 3 (CDR3) of T cells receptor on ovarian cancer cells and the involved mechanisms. METHODS: IP10 and CDR3 were linked with single-chain antibody (scfv) and exotoxin gene...

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Detalles Bibliográficos
Autores principales: Chen, Qi, He, Quan, Zhuang, Lingling, Wang, Kunya, Yin, Chunhua, He, Linsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859960/
https://www.ncbi.nlm.nih.gov/pubmed/32009802
http://dx.doi.org/10.2147/OTT.S209757