Long-read sequencing and haplotype linkage analysis enabled preimplantation genetic testing for patients carrying pathogenic inversions

BACKGROUND: Preimplantation genetic testing (PGT) has already been applied in patients known to carry chromosomal structural variants to improve the clinical outcome of assisted reproduction. However, conventional molecular techniques are not capable of reliably distinguishing embryos that carry bal...

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Detalles Bibliográficos
Autores principales: Zhang, Shuo, Liang, Fan, Lei, Caixia, Wu, Junping, Fu, Jing, Yang, Qi, Luo, Xiao, Yu, Guoliang, Wang, Depeng, Zhang, Yueping, Lu, Daru, Sun, Xiaoxi, Liang, Yu, Xu, Congjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Chromosomal Rearrangements
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860410/
https://www.ncbi.nlm.nih.gov/pubmed/31439719
http://dx.doi.org/10.1136/jmedgenet-2018-105976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860410/
https://www.ncbi.nlm.nih.gov/pubmed/31439719
http://dx.doi.org/10.1136/jmedgenet-2018-105976

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