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A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology
Macrophages respond to signals in the microenvironment by changing their functional phenotypes, a process known as polarization. Depending on the context, they acquire different patterns of transcriptional activation, cytokine expression and cellular metabolism which collectively constitute a contin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860420/ https://www.ncbi.nlm.nih.gov/pubmed/31738746 http://dx.doi.org/10.1371/journal.pcbi.1007468 |