IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

The interleukin (IL)-1 family of cytokines is strongly associated with systemic sclerosis (SSc) and pulmonary involvement, but the molecular mechanisms are poorly understood. The aim of this study was to assess the role of IL-1α and IL-1β in pulmonary vascular and interstitial remodelling in a mouse...

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Detalles Bibliográficos
Autores principales: Birnhuber, Anna, Crnkovic, Slaven, Biasin, Valentina, Marsh, Leigh M., Odler, Balazs, Sahu-Osen, Anita, Stacher-Priehse, Elvira, Brcic, Luka, Schneider, Frank, Cikes, Nada, Ghanim, Bahil, Klepetko, Walter, Graninger, Winfried, Allanore, Yannick, Eferl, Robert, Olschewski, Andrea, Olschewski, Horst, Kwapiszewska, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860995/
https://www.ncbi.nlm.nih.gov/pubmed/31320452
http://dx.doi.org/10.1183/13993003.00154-2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860995/
https://www.ncbi.nlm.nih.gov/pubmed/31320452
http://dx.doi.org/10.1183/13993003.00154-2019

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