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Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability

Mask family proteins were discovered in Drosophila to promote the activity of the transcriptional coactivator Yorkie (Yki), the sole fly homolog of mammalian YAP (YAP1) and TAZ (WWTR1). The molecular function of Mask, or its mammalian homologs Mask1 (ANKHD1) and Mask2 (ANKRD17), remains unclear. Mas...

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Detalles Bibliográficos
Autores principales: Sidor, Clara, Borreguero-Munoz, Nerea, Fletcher, Georgina C, Elbediwy, Ahmed, Guillermin, Oriane, Thompson, Barry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861002/
https://www.ncbi.nlm.nih.gov/pubmed/31661072
http://dx.doi.org/10.7554/eLife.48601