A proline-rich motif on VGLUT1 reduces synaptic vesicle super-pool and spontaneous release frequency

Glutamate secretion at excitatory synapses is tightly regulated to allow for the precise tuning of synaptic strength. Vesicular Glutamate Transporters (VGLUT) accumulate glutamate into synaptic vesicles (SV) and thereby regulate quantal size. Further, the number of release sites and the release prob...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao Min, François, Urielle, Silm, Kätlin, Angelo, Maria Florencia, Fernandez-Busch, Maria Victoria, Maged, Mona, Martin, Christelle, Bernard, Véronique, Cordelières, Fabrice P, Deshors, Melissa, Pons, Stéphanie, Maskos, Uwe, Bemelmans, Alexis Pierre, Wojcik, Sonja M, El Mestikawy, Salah, Humeau, Yann, Herzog, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861006/
https://www.ncbi.nlm.nih.gov/pubmed/31663854
http://dx.doi.org/10.7554/eLife.50401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861006/
https://www.ncbi.nlm.nih.gov/pubmed/31663854
http://dx.doi.org/10.7554/eLife.50401

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