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A proline-rich motif on VGLUT1 reduces synaptic vesicle super-pool and spontaneous release frequency
Glutamate secretion at excitatory synapses is tightly regulated to allow for the precise tuning of synaptic strength. Vesicular Glutamate Transporters (VGLUT) accumulate glutamate into synaptic vesicles (SV) and thereby regulate quantal size. Further, the number of release sites and the release prob...
Autores principales: | Zhang, Xiao Min, François, Urielle, Silm, Kätlin, Angelo, Maria Florencia, Fernandez-Busch, Maria Victoria, Maged, Mona, Martin, Christelle, Bernard, Véronique, Cordelières, Fabrice P, Deshors, Melissa, Pons, Stéphanie, Maskos, Uwe, Bemelmans, Alexis Pierre, Wojcik, Sonja M, El Mestikawy, Salah, Humeau, Yann, Herzog, Etienne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861006/ https://www.ncbi.nlm.nih.gov/pubmed/31663854 http://dx.doi.org/10.7554/eLife.50401 |
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