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Deficiency of C3a receptor attenuates the development of diabetic nephropathy

OBJECTIVE: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and end-stage renal disease. Emerging evidence suggests that complement activation is involved in the pathogenesis of DN. The aim of this study was to investigate the pathogenic role of C3a and C3a receptor (C3aR) in...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Qian, Chang, Dong-Yuan, Chen, Min, Zhao, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861086/
https://www.ncbi.nlm.nih.gov/pubmed/31798904
http://dx.doi.org/10.1136/bmjdrc-2019-000817