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Deficiency of C3a receptor attenuates the development of diabetic nephropathy
OBJECTIVE: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and end-stage renal disease. Emerging evidence suggests that complement activation is involved in the pathogenesis of DN. The aim of this study was to investigate the pathogenic role of C3a and C3a receptor (C3aR) in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861086/ https://www.ncbi.nlm.nih.gov/pubmed/31798904 http://dx.doi.org/10.1136/bmjdrc-2019-000817 |