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JAK/STAT Cytokine Signaling at the Crossroad of NK Cell Development and Maturation

Natural Killer (NK) cells are cytotoxic lymphocytes of the innate immune system and play a critical role in anti-viral and anti-tumor responses. NK cells develop in the bone marrow from hematopoietic stem cells (HSCs) that differentiate through common lymphoid progenitors (CLPs) to NK lineage-restri...

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Detalles Bibliográficos
Autores principales: Gotthardt, Dagmar, Trifinopoulos, Jana, Sexl, Veronika, Putz, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861185/
https://www.ncbi.nlm.nih.gov/pubmed/31781102
http://dx.doi.org/10.3389/fimmu.2019.02590