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Commonly used estimates of the genetic contribution to disease are subject to the same fallacies as bad luck estimates

The scientific debate following the initial formulation of the “bad luck” hypothesis in cancer development highlighted how measures based on analysis of variance are inappropriately used for risk communication. The notion of “explained” variance is not only used to quantify randomness, but also to q...

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Detalles Bibliográficos
Autores principales: Björk, Jonas, Andersson, Tomas, Ahlbom, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861200/
https://www.ncbi.nlm.nih.gov/pubmed/31641918
http://dx.doi.org/10.1007/s10654-019-00573-8