Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity

Alveolar epithelial injury induced by reactive oxygen species (ROS) and abnormal collagen production by activated fibroblasts (myofibroblasts) is involved in the onset and exacerbation of idiopathic pulmonary fibrosis (IPF). Compared with alveolar epithelial cells, lung fibroblasts, especially myofi...

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Detalles Bibliográficos
Autores principales: Sugizaki, Toshifumi, Tanaka, Ken-ichiro, Asano, Teita, Kobayashi, Daisuke, Hino, Yuuki, Takafuji, Ayaka, Shimoda, Mikako, Mogushi, Kaoru, Kawahara, Masahiro, Mizushima, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861265/
https://www.ncbi.nlm.nih.gov/pubmed/31754474
http://dx.doi.org/10.1038/s41420-019-0226-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861265/
https://www.ncbi.nlm.nih.gov/pubmed/31754474
http://dx.doi.org/10.1038/s41420-019-0226-y

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