Cargando…

Quorum sensing modulates the formation of virulent Legionella persisters within infected cells

The facultative intracellular bacterium Legionella pneumophila replicates in environmental amoebae and in lung macrophages, and causes Legionnaires’ disease. Here we show that L. pneumophila reversibly forms replicating and nonreplicating subpopulations of similar size within amoebae. The nonreplica...

Descripción completa

Detalles Bibliográficos
Autores principales: Personnic, Nicolas, Striednig, Bianca, Lezan, Emmanuelle, Manske, Christian, Welin, Amanda, Schmidt, Alexander, Hilbi, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861284/
https://www.ncbi.nlm.nih.gov/pubmed/31740681
http://dx.doi.org/10.1038/s41467-019-13021-8