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Quorum sensing modulates the formation of virulent Legionella persisters within infected cells
The facultative intracellular bacterium Legionella pneumophila replicates in environmental amoebae and in lung macrophages, and causes Legionnaires’ disease. Here we show that L. pneumophila reversibly forms replicating and nonreplicating subpopulations of similar size within amoebae. The nonreplica...
Autores principales: | Personnic, Nicolas, Striednig, Bianca, Lezan, Emmanuelle, Manske, Christian, Welin, Amanda, Schmidt, Alexander, Hilbi, Hubert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861284/ https://www.ncbi.nlm.nih.gov/pubmed/31740681 http://dx.doi.org/10.1038/s41467-019-13021-8 |
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