Integration of TGF-β-induced Smad signaling in the insulin-induced transcriptional response in endothelial cells

Insulin signaling governs many processes including glucose homeostasis and metabolism, and is therapeutically used to treat hyperglycemia in diabetes. We demonstrated that insulin-induced Akt activation enhances the sensitivity to TGF-β by directing an increase in cell surface TGF-β receptors from a...

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Detalles Bibliográficos
Autores principales: Budi, Erine H., Hoffman, Steven, Gao, Shaojian, Zhang, Ying E., Derynck, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861289/
https://www.ncbi.nlm.nih.gov/pubmed/31740700
http://dx.doi.org/10.1038/s41598-019-53490-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861289/
https://www.ncbi.nlm.nih.gov/pubmed/31740700
http://dx.doi.org/10.1038/s41598-019-53490-x

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