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Multicentric analytical comparability study of programmed death-ligand 1 expression on tumor-infiltrating immune cells and tumor cells in urothelial bladder cancer using four clinically developed immunohistochemistry assays

Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) correlated in several studies with PD-L1/programmed death-1 (PD-1) checkpoint inhibitor efficacy. Since June 2018, a positive PD-L1 status is required for atezolizumab or pembrolizumab treatment...

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Detalles Bibliográficos
Autores principales: Schwamborn, Kristina, Ammann, Johannes U, Knüchel, Ruth, Hartmann, Arndt, Baretton, Gustavo, Lasitschka, Felix, Schirmacher, Peter, Braunschweig, Till, Tauber, Robert, Erlmeier, Franziska, Hieke-Schulz, Stefanie, Weichert, Wilko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861354/
https://www.ncbi.nlm.nih.gov/pubmed/31267201
http://dx.doi.org/10.1007/s00428-019-02610-z