Fenofibrate increases very-long-chain sphingolipids and improves blood glucose homeostasis in NOD mice

AIMS/HYPOTHESIS: Sphingolipid metabolism regulates beta cell biology and inflammation and is abnormal at the onset of type 1 diabetes. Fenofibrate, a regulator of sphingolipid metabolism, is known to prevent diabetes in NOD mice. Here, we aimed to investigate the effects of fenofibrate on the pancre...

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Detalles Bibliográficos
Autores principales: Holm, Laurits J., Haupt-Jorgensen, Martin, Giacobini, Jano D., Hasselby, Jane P., Bilgin, Mesut, Buschard, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861358/
https://www.ncbi.nlm.nih.gov/pubmed/31410530
http://dx.doi.org/10.1007/s00125-019-04973-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861358/
https://www.ncbi.nlm.nih.gov/pubmed/31410530
http://dx.doi.org/10.1007/s00125-019-04973-z

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