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Tau Phosphorylation in a Mouse Model of Temporal Lobe Epilepsy

Hyperphosphorylation of the microtubule-associated protein tau and its resultant aggregation into neurofibrillary tangles (NFT) is a pathological characteristic of neurodegenerative disorders known as tauopathies. Tau is a neuronal protein involved in the stabilization of microtubule structures of t...

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Detalles Bibliográficos
Autores principales: Alves, Marianna, Kenny, Aidan, de Leo, Gioacchino, Beamer, Edward H., Engel, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861366/
https://www.ncbi.nlm.nih.gov/pubmed/31780921
http://dx.doi.org/10.3389/fnagi.2019.00308