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Correlations between microsatellite instability and the biological behaviour of tumours

PURPOSE: Microsatellites are widely distributed repetitive DNA motifs, accounting for approximately 3% of the genome. Due to mismatch repair system deficiency, insertion or deletion of repetitive units often occurs, leading to microsatellite instability. In this review, we aimed to explore the relat...

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Detalles Bibliográficos
Autores principales: Yang, Guang, Zheng, Ru-yi, Jin, Zai-shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861542/
https://www.ncbi.nlm.nih.gov/pubmed/31617076
http://dx.doi.org/10.1007/s00432-019-03053-4