Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression.

Bone destructive diseases such as periodontitis and rheumatoid arthritis are caused by excessive activation of osteoclasts. Osteoclastogenesis is regulated by Receptor activator of nuclear factor kappa-β ligand (RANKL) produced by osteoclastogenesis supporting cells such as osteoblast and osteocyte....

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Detalles Bibliográficos
Autores principales: Narimiya, Tsuyoshi, Kanzaki, Hiroyuki, Yamaguchi, Yuki, Wada, Satoshi, Katsumata, Yuta, Tanaka, Ken, Tomonari, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861591/
https://www.ncbi.nlm.nih.gov/pubmed/31763378
http://dx.doi.org/10.1016/j.bonr.2019.100228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861591/
https://www.ncbi.nlm.nih.gov/pubmed/31763378
http://dx.doi.org/10.1016/j.bonr.2019.100228

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