Inhibition of lncRNA XIST Improves Myocardial I/R Injury by Targeting miR-133a through Inhibition of Autophagy and Regulation of SOCS2

The objective of this study was to investigate the role of lncRNA XIST and its relationship with miR-133a in myocardial I/R injury. H9C2 cells treated by hypoxia/reoxygenation (H/R) were used to establish an in vitro I/R model. The small interfering RNA (siRNA) for XIST and miR-133 mimics, inhibitor...

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Detalles Bibliográficos
Autores principales: Li, Zhiqiang, Zhang, Yaping, Ding, Nan, Zhao, Yudong, Ye, Zankai, Shen, Lei, Yi, Hanlu, Zhu, Yaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861669/
https://www.ncbi.nlm.nih.gov/pubmed/31734557
http://dx.doi.org/10.1016/j.omtn.2019.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861669/
https://www.ncbi.nlm.nih.gov/pubmed/31734557
http://dx.doi.org/10.1016/j.omtn.2019.10.004

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