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Inhibition of lncRNA XIST Improves Myocardial I/R Injury by Targeting miR-133a through Inhibition of Autophagy and Regulation of SOCS2
The objective of this study was to investigate the role of lncRNA XIST and its relationship with miR-133a in myocardial I/R injury. H9C2 cells treated by hypoxia/reoxygenation (H/R) were used to establish an in vitro I/R model. The small interfering RNA (siRNA) for XIST and miR-133 mimics, inhibitor...
Autores principales: | Li, Zhiqiang, Zhang, Yaping, Ding, Nan, Zhao, Yudong, Ye, Zankai, Shen, Lei, Yi, Hanlu, Zhu, Yaobin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861669/ https://www.ncbi.nlm.nih.gov/pubmed/31734557 http://dx.doi.org/10.1016/j.omtn.2019.10.004 |
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