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The role of MHC class I recycling and Arf6 in cross-presentation by murine dendritic cells

Cross-presentation by MHC class I molecules (MHC-I) is critical for priming of cytotoxic T cells. Peptides derived from cross-presented antigens can be loaded on MHC-I in the endoplasmic reticulum and in endocytic or phagocytic compartments of murine DCs. However, the origin of MHC-I in the latter c...

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Detalles Bibliográficos
Autores principales: Montealegre, Sebastian, Abramova, Anastasia, Manceau, Valerie, de Kanter, Anne-Floor, van Endert, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861705/
https://www.ncbi.nlm.nih.gov/pubmed/31740564
http://dx.doi.org/10.26508/lsa.201900464