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Population pharmacokinetics of tacrolimus in pediatric patients with systemic-onset juvenile idiopathic arthritis: Initial dosage recommendations

Pediatric patients with systemic-onset juvenile idiopathic arthritis (SOJIA) may be treated with tacrolimus. However, the therapeutic range for tacrolimus is narrow with considerable inter- and intra-individual variability, making it difficult to formulate an ideal dosage regimen for personalized tr...

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Detalles Bibliográficos
Autores principales: Wang, Dongdong, Chen, Xiao, Xu, Hong, Li, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861867/
https://www.ncbi.nlm.nih.gov/pubmed/31772640
http://dx.doi.org/10.3892/etm.2019.8129