Icariin reduces high glucose-induced endothelial progenitor cell dysfunction via inhibiting the p38/CREB pathway and activating the Akt/eNOS/NO pathway

High glucose (HG) impairs endothelial progenitor cell (EPC) function. The activation of p38 mitogen-activated protein kinase and the inhibition of the Akt/eNOS/NO pathway serve central roles in this process. Icariin has protective effects in endothelial cells. The aim of the present study was to inv...

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Detalles Bibliográficos
Autores principales: Chen, Sisi, Wang, Zhenya, Zhou, Heng, He, Bo, Hu, Dan, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861942/
https://www.ncbi.nlm.nih.gov/pubmed/31772646
http://dx.doi.org/10.3892/etm.2019.8132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861942/
https://www.ncbi.nlm.nih.gov/pubmed/31772646
http://dx.doi.org/10.3892/etm.2019.8132

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