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Icariin reduces high glucose-induced endothelial progenitor cell dysfunction via inhibiting the p38/CREB pathway and activating the Akt/eNOS/NO pathway
High glucose (HG) impairs endothelial progenitor cell (EPC) function. The activation of p38 mitogen-activated protein kinase and the inhibition of the Akt/eNOS/NO pathway serve central roles in this process. Icariin has protective effects in endothelial cells. The aim of the present study was to inv...
Autores principales: | Chen, Sisi, Wang, Zhenya, Zhou, Heng, He, Bo, Hu, Dan, Jiang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861942/ https://www.ncbi.nlm.nih.gov/pubmed/31772646 http://dx.doi.org/10.3892/etm.2019.8132 |
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