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IGF-1 Inhibits Apoptosis of Porcine Primary Granulosa Cell by Targeting Degradation of Bim(EL)

Insulin-like growth factor-1 (IGF-1) is an intra-ovarian growth factor that plays important endocrine or paracrine roles during ovarian development. IGF-1 affects ovarian function and female fertility through reducing apoptosis of granulosa cells, yet the underlying mechanism remains poorly characte...

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Detalles Bibliográficos
Autores principales: Han, Ying, Wang, Shumin, Wang, Yingzheng, Zeng, Shenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861984/
https://www.ncbi.nlm.nih.gov/pubmed/31661816
http://dx.doi.org/10.3390/ijms20215356