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Aberrant Epigenomic Modulation of Glucocorticoid Receptor Gene (NR3C1) in Early Life Stress and Major Depressive Disorder Correlation: Systematic Review and Quantitative Evidence Synthesis

Early life stress (ELS) induced by psychological trauma, child maltreatment, maternal separation, and domestic violence predisposes to psycho-behavioral pathologies during adulthood, namely major depressive disorder (MDD), anxiety, and bipolar affective disorder. While environmental data are availab...

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Detalles Bibliográficos
Autores principales: Holmes, Laurens, Shutman, Emily, Chinaka, Chinacherem, Deepika, Kerti, Pelaez, Lavisha, Dabney, Kirk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861987/
https://www.ncbi.nlm.nih.gov/pubmed/31689998
http://dx.doi.org/10.3390/ijerph16214280