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Proteomic Analysis of Urinary Extracellular Vesicles Reveals a Role for the Complement System in Medullary Sponge Kidney Disease

Medullary sponge kidney (MSK) disease is a rare and neglected kidney condition often associated with nephrocalcinosis/nephrolithiasis and cystic anomalies in the precalyceal ducts. Little is known about the pathogenesis of this disease, so we addressed the knowledge gap using a proteomics approach....

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Detalles Bibliográficos
Autores principales: Bruschi, Maurizio, Granata, Simona, Candiano, Giovanni, Fabris, Antonia, Petretto, Andrea, Ghiggeri, Gian Marco, Gambaro, Giovanni, Zaza, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862015/
https://www.ncbi.nlm.nih.gov/pubmed/31694344
http://dx.doi.org/10.3390/ijms20215517