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Coix Seed Extract Enhances the Anti-Pancreatic Cancer Efficacy of Gemcitabine through Regulating ABCB1- and ABCG2-Mediated Drug Efflux: A Bioluminescent Pharmacokinetic and Pharmacodynamic Study

A deep insight into the function and kinetics of ATP-binding cassette (ABC) transporters may aid in the development of pharmaceutics that can minimize the particular facet of chemo-resistance. We utilized bioluminescence imaging to monitor the ABC transporter mediated intracellular drug efflux funct...

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Detalles Bibliográficos
Autores principales: Qian, Yifan, Xiong, Yang, Feng, Di, Wu, Yali, Zhang, Xu, Chen, Liping, Gu, Mancang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862065/
https://www.ncbi.nlm.nih.gov/pubmed/31652737
http://dx.doi.org/10.3390/ijms20215250