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USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In Vitro

The ubiquitin–proteasome system is an essential regulator of several cellular pathways involving oncogenes. Deubiquitination negatively regulates target proteins or substrates linked to both hereditary and sporadic forms of cancer. The deubiquitinating enzyme ubiquitin-specific protease 14 (USP14) i...

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Detalles Bibliográficos
Autores principales: Han, Kyung Ho, Kwak, Minseok, Lee, Tae Hyeong, Park, Min-soo, Jeong, In-ho, Kim, Min Ji, Jin, Jun-O, Lee, Peter Chang-Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862215/
https://www.ncbi.nlm.nih.gov/pubmed/31653087
http://dx.doi.org/10.3390/ijms20215300